• 专利附录
  • 专利说明
  • 权利要求
  • 类似技术
  • 同族专利
  • 引用文献
  • 法律状态
  • 优先权
    • 专利摘要:
    INJECTION DEVICE FOR INJECTING LIQUID MEDICINE TO A PATIENT. The injection device comprises: a static structure (2) comprising a first gear member (14), a dynamic structure (3) comprising a medicine container (11), means (6, 7, 8, 12) for pushing the liquid medicine out of said medicine container (11) for its injection to a patient, and a second gear member (13) engaged with the first gear member (14), a drive member (4) for driving a ( 14) of the first and second gear members (13, 14) so as to cause the dynamic structure (3) to move relative to the static structure (2) along a predetermined direction (D) due to the engagement between the first and second gear members (13, 14), and clamping means (23, 25, 28) for maintaining engagement between the first and second gear members (13, 14) in normal condition of the injection device, and to allow disengagement of the first and second transmission members (13, 14) upon a shock r received by the injection device along the predetermined direction (D).
    公开号:BR112014029246B1
    申请号:R112014029246-9
    申请日:2013-06-11
    公开日:2021-08-10
    发明作者:Werner Wurmbauer；Josef Schopf；Bernhard Schatz
    申请人:Ares Trading S.A.；
    IPC主号:
    专利说明:

    [0001] The present invention relates to an injection device for injecting liquid medicine to a patient, of the type comprising a medicine container, such as a cartridge, connectable to a needle.
    [0002] WO 2005/077441 describes a device comprising, within a housing, a cartridge holder for receiving and supporting a cartridge, first electromechanical means for axially moving a cartridge plunger for dispensing medicine to a patient, and the second electromechanical means for axially moving a structure including the cartridge holder and first electromechanical means for retracting the cartridge with the needle connected thereto in the housing when not in use and moving the cartridge with the needle towards the outside of the housing to pierce the patient's skin and inject a dose of medicine.
    [0003] A problem with such a device is that the interface between said structure and the second electromechanical means is sensitive to shocks received by the device, especially in the axial direction. Thus, if the device is lowered there is a risk that the connection between said structure and the second electromechanical means will break.
    [0004] The present invention aims to remedy this problem, at least partially. To this end, there is provided an injection device for injecting liquid medicine to a patient, comprising: - a housing, - a static structure comprising a first gear member, - a dynamic structure comprising a medicine container, means for pushing medicine liquid from said medicament container for its injection to a patient, and a second gear member engaged with the first gear member; a drive member for driving one of the first and second gear members so as to cause the dynamic structure moves relative to the static structure along a predetermined direction due to the engagement between the first and second gear members, and tightening means for maintaining the engagement between the first and second gear members in normal condition of the injection device , and to allow disengagement of the first and second gear members upon a shock received by the i. Injection along the predetermined direction, said clamping means comprising:- means for allowing the other of the first and second gear members to move away from said one of the first and second gear members and thus disengage from said one. of the first and second gear members, - a locking member which, in a predetermined position, prevents the other of the first and second gear members from moving away from said one of the first and second gear members, and - a return spring to keep the locking member in the predetermined position, the force of said return spring being overcome by the other of the first and second gear members upon a shock received by the injection device along the predetermined direction and moving the other of the first and second members away from said one of the first and second gear members.
    [0005] Typically, said one of the first and second gear members is a wheel and the other of the first and second gear members is a rack.
    [0006] In a preferred embodiment, the drive member is mounted on the static frame and said one of the first and second gear members is the first gear member.
    [0007] The means for allowing the other of the first and second gear members to move out of said one of the first and second gear members may comprise at least one flexible member, through which the other of the first and second members gear is mounted on the injection device.
    [0008] Advantageously, the predetermined position of the locking member is a rest position in which the locking member is held by the return spring against a stop member.
    [0009] The stop member may be a pin engaged in an oblong opening of the locking member.
    [00010] The locking member can be a lever.
    [00011] The drive member can be a motor.
    [00012] The means for pushing liquid medicine out of the medicine container may comprise a piston rod, a transmission for driving the piston rod and a second drive member for driving the transmission. The second drive member can be a motor.
    [00013] Other features and advantages of the present invention will become evident after reading the following detailed description made with reference to the attached schematic figure, which shows an injection device according to a preferred embodiment of the invention.
    [00014] In the following, the term "wheel" will indistinctly designate a wheel or a pinion.
    [00015] With reference to the attached figure, an injection device according to the present invention comprises, within a housing 1, a static structure 2, that is, a structure that as a whole is fixed in relation to housing 1 , and a dynamic structure 3, that is, a structure as a whole, which is movable relative to the housing 1. The static structure 2 is shown in solid lines. Dynamic structure 3 is shown in dashed lines. Static structure 2 comprises a body (not shown) and, mounted on the body, a motor 4 and a transmission or gearbox 5 driven by the motor 4. The dynamic structure 3 comprises a body (not shown) and, mounted thereon. body, a motor 6, a transmission 7 driven by the motor 6, a piston rod 8 and a cartridge holder 9. The dynamic structure 3 is movable in the longitudinal direction D of the device inside the body of the static part 2. The housing 1 it has a port 10 to allow insertion or removal of a medicament cartridge 11 into/from the device, for example, in the manner described in WO 2005/077441. When inserted into the device, the medication cartridge 11 is supported by the cartridge holder 9. The needle 12 is connectable to the cartridge 11 at one end thereof. The plunger rod 8 and, when inserted into the device, the cartridge 11 and the needle 12 all extend in the longitudinal direction D.
    [00016] For its displacement in relation to the housing 1 and the static structure 2, the dynamic structure 3 comprises a rack 13 that extends along the longitudinal direction D and that engages with a gear wheel 14 of the transmission 5. the actuation of motor 4 moves rack 13 and with it dynamic structure 3 towards or away from a skin contact wall 15 of housing 1 depending on the direction of rotation of motor shaft 4. The dynamic structure 3 can be moved between a retracted position in which the needle 12 is fully in the housing 1 (as shown in the drawing), thus protecting the user from the risk of injury, and an operating position in which the needle 12 protrudes out of the housing 1 through an opening 16 provided in the skin contacting wall 15 for piercing the patient's skin.
    [00017] The piston rod 8 can be displaced along the longitudinal direction D with respect to the body of the dynamic structure 3 by actuation of the motor 6. For this purpose, in a manner known per se, one of the transmission gear wheels 17 7 has an internal thread (not shown) that cooperates with a thread provided on the surface of the rod 8, and an annular locking member (not shown) fixed to the body of the dynamic structure 3 has internal projections that cooperate with longitudinal grooves of the piston rod 8 to prevent the 8 piston rod from rotating. Thus, the actuation of the motor 6 moves the piston rod 8 towards or away from the skin contacting wall 15 depending on the direction of rotation of the motor shaft 6. When moved in the direction of the skin contacting wall 15 , the plunger rod 8 drives a plunger 18 in the cartridge 11, which in turn drives the liquid medicine 19 out of the cartridge 11 through the needle 12 to effect the injection.
    [00018] A control unit 20 provided in the device can control the motors 4, 6, so as to carry out a sequence comprising a first step in which the dynamic structure 3 is moved from its retracted position to its operating position, a second stage in which the plunger rod 8 is moved to carry out the injection and a third stage in which the dynamic structure 3 is moved back to its retracted position after the injection of a given dose has been performed. Said sequence is triggered by the control unit 20 only after a sensor (which may be of the type described in WO 2007/088444) has detected that the device is placed on the patient's skin and after an injection button 21 has been pressed by the patient. The movement capability of the dynamic structure 3 can also be used to connect the needle 12 to the cartridge 11, prior to use of the device, in the manner described in WO 2005/077441.
    [00019] According to the present invention, clamping means are provided to protect the interface between the static and dynamic structures 2, 3, i.e. the part of the device including the rack 13 and the gear wheel 14, from received shocks by the device. In fact, in the case of shocks subjecting the device to forces oriented along the longitudinal direction D, typically in case the device is lowered, the rack 13 and/or the gear wheel 14 may break due to the engagement of the teeth of the rack 13 with the teeth of the gear wheel 14 and due to the weight of the dynamic frame 3. To avoid this, the rack 13 is elastically mounted on the body of the dynamic frame 3 and can thus tilt with respect to the longitudinal direction D, as shown by arrow 22. More precisely, the rack 13 is connected via flexible arms 23 to a plate 24 fixed to the body of the dynamic structure 3. The rack 13, the arms 23 and the plate 24 can be part of a single piece. Arms 23 can flex transversely to the longitudinal direction D and cause rack 13 to tilt. In normal condition, or use of the device, rack 13 is held parallel to longitudinal direction D by lever 25. Lever 25 is mounted on static frame 2, around pivot 26, and has a contact surface 27 against which the rear surface of the rack 13, i.e. the surface opposite the toothed rack surface, can rest. The lever 25 is subjected to the action of a return spring 28 mounted on the static frame 2. The spring 28 holds the lever 25 against the stop pin 29 fixed on the static frame 2 and engaged in an oblong opening 30 of the lever 25. rest position, lever 25 prevents rack 13 from disengaging from gear wheel 14, without pressing rack 13 against gear wheel 14, thanks to stop pin 29, thus avoiding friction losses during normal displacements of the rack 13. When a shock is received by the device along the longitudinal direction D, the teeth of rack 3 engaged with teeth of gear wheel 14 slide over teeth of gear wheel 14, causing rack 13 to move away from gear wheel 14 in the direction of arrow 22, due to the shape of the teeth (which may be of conventional type). During this movement of the rack 13, the lever 25 is driven by the rack 13 and caused to rotate against the force of the spring 28 within the range of movement allowed by the pin 29 and the oblong opening 30. The rack 13 is thus disengaged from the wheel of gear 14 so that the dynamic structure 3 is free to move along the longitudinal direction D under the force generated by the shock. Since the shock is too much, spring 28 returns lever 25 and rack 13 to their normal position, where rack 13 is engaged with gear wheel 14. It is noted that stop pin 29 limits movement of the lever 25 and thus protects the rack 13 and the flexible arms 23 during impact. After the shock, resetting of the device can be performed to move the dynamic structure 3 back to the position where it was before the shock, i.e. generally the retracted position.
    [00020] Thus, the flexible arms 23, the lever 25 and the return spring 28 define clamping means that maintain engagement between the rack 13 and the gear wheel 14 under normal conditions, but allow the rack 13 to disengage from the wheel of gear 14 over a shock received by the device in the longitudinal direction D. Thanks to the present invention, the most shock-sensitive portion of the device is protected.
    [00021] The present invention has been described above by way of example only. It will be apparent to one skilled in the art that modifications can be made without departing from the scope of the appended claims. For example, rack 13 can be mounted on static frame 2 and motor 4, transmission 5, lever 25 and return spring 28 can be mounted on dynamic frame 3. According to another modification, rack 13 it can be mounted on the device so as to be translationally movable transversely to the D direction, instead of being elastically mounted via the flexible arms 23.
    权利要求:
    Claims (11)
    [0001]
    1. Injection device for injecting liquid medicine to a patient, comprising: - a housing (1), - a static structure (2), comprising a first gear member (14), - a dynamic structure (3) comprising a medicine container (11), means (6, 7, 8) for propelling liquid medicine from said medicine container (11) for its injection to a patient, and a second gear member (13) engaged with the first gear member (14), - a drive member (4) for driving one of the first and second gear members (14, 13) so as to make the dynamic structure (3) move relative to the static structure (2), along a predetermined direction (D), due to the engagement between the first and second gear members (14, 13), and clamping means (28) for maintaining the engagement between the first and second gear members (14, 13) in normal condition of the injection device, and to allow disengagement of the first and second gear members (14, 13) on a shock received by the injection device along the predetermined direction (D), characterized in that the clamping means comprises: a return spring (28) which prevents the other of the first and second gear members (14, 13) moves away from said one of the first and second gear members (14, 13), the force of said return spring (28) being overcome by the other of the first and second gear members ( 14, 13) after a shock received by the injection device along the predetermined direction (D) and away from the other of the first and second gear elements (14, 13) from said one of the first and second gear members (14, 13 ).
    [0002]
    2. Injection device according to claim 1 characterized in that said clamping means further comprises:- means (23) for allowing the other of the first and second gear members (14, 13) to move away from said one of the first and second gear members (14, 13) and thus disengages from said one of the first and second gear members (14, 13), and a locking member (25) which, in a predetermined position, prevents the other of the first and second gear members (14, 13) from moving away from said one of the first and second gear members (14, 13).
    [0003]
    3. Injection device according to claim 1 or 2, characterized in that said one of the first and second gear members (14, 13) is a wheel (14) and the other one of the first and second gear members (14, 13) is a rack (13).
    [0004]
    4. Injection device according to any one of claims 1 to 3, characterized in that the drive member (4) is mounted on the static structure (2) and said one of the first and second gear members (14 13) is the first gear member (14).
    [0005]
    5. Injection device according to any one of claims 1 to 4, characterized in that the means (23) for allowing the other of the first and second gear members (14, 13) to move out of a Said one of the first and second gear members (14, 13) comprises at least one flexible member (23), through which the other of the first and second gear members (14, 13) is mounted on the injection device.
    [0006]
    6. Injection device according to claim 5, characterized in that the predetermined position of the locking member (23) is a rest position, in which the locking member (25) is held by the return spring (28 ) against a stop member (29).
    [0007]
    7. Injection device according to claim 6, characterized in that the stop member (29) is a pin engaged in an oblong opening (30) of the locking member (25).
    [0008]
    8. Injection device according to any one of claims 1 to 7, characterized in that the locking member (25) is a lever.
    [0009]
    9. Injection device according to any one of claims 1 to 8, characterized in that the drive member (4) is a motor.
    [0010]
    10. Injection device according to any one of claims 1 to 9, characterized in that the means (6, 7, 8) for pushing liquid medicine out of the medicine container (11) comprise a piston rod (8) , a transmission (7) to drive the piston rod (8) and a second drive member (6) to drive the transmission (7).
    [0011]
    11. Injection device according to claim 10, characterized in that the second drive member (6) is a motor.
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    法律状态:
    2018-12-04| B06F| Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]|
    2019-12-10| B06U| Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]|
    2021-04-06| B06A| Patent application procedure suspended [chapter 6.1 patent gazette]|
    2021-07-20| B09A| Decision: intention to grant [chapter 9.1 patent gazette]|
    2021-08-10| B16A| Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]|Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 11/06/2013, OBSERVADAS AS CONDICOES LEGAIS. |
    优先权:
    申请号 | 申请日 | 专利标题
    EP12004542.2|2012-06-15|
    EP12004542.2A|EP2674180A1|2012-06-15|2012-06-15|Injection device|
    PCT/IB2013/001212|WO2013186617A1|2012-06-15|2013-06-11|Injection device|
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